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陈磊 助理教授

来源:yl8cc永利 发布时间:2019-07-29 10:13:18


陈磊,男,1988年8月生,河南信阳人。2019年6月毕业于西安交通大学,获生物学博士学位,现为yl8cc永利青年卓越人才。

一、主要研究方向

   1. 代谢综合征对表观遗传的影响

   2. 功能性天然产物对线粒体功能的影响

   3. DNA表观遗传修饰失调介导的神经损伤

二、代表性研究成果

[1] Lei Chen, Lei Liu, Caixia Li, ChengLi Hu, Fan Su, Run Liu, Mengqi Zeng, Daina Zhao, Jiankang Liu, Yurong Guo and Jiangang Long. A mix of apple pomace polysaccharide improves mitochondrial function and reduces oxidative stress in the liver high-fat diet-induced obese mice [J]. Molecular Nutrition & Food Research, 2017, 61(3):1600433.

 [2] Lei Chen, Xi Yang, Run Liu, Lei Liu, Daina Zhao, Jiankang Liu, Yurong Guo and Jiangang Long. Thinned-young apple polysaccharides improve hepatic metabolic disorder in high-fat diet-induced obese mice via activating mitochondrial respiratory function [J]. Journal of Functional Foods, 2017, 33:396-407.

[3] Ouyang Cheng, Chen Lei, Rees Thomas, Chen Yu, Liu J, Ji Liang-Nian, Long Jiangang, Chao Hui. A mitochondria-targeting hetero-binuclear Ir (III)-Pt (II) complex induces necrosis in cisplatin-resistant tumor cells [J]. Chemical Communications, 2018; 54; 49: p6268-p6271.

[4] Lijun Sun, Jiaojiao Sun, Lei Chen, Pengfei Niu, Xingbin Yang, Yurong Guo. Preparation and characterization of chitosan film incorporated with thinned young apple polyphenols as an active packaging material. Carbohydrate Polymers, 2017, 163: 81-91.

[5] Yibin Liu, Paulina Siejka, Gergana Velikova, Fang Yuan, Marketa Tomkova, Chunsen Bai, Lei Chen, Ying Bi, Benjamin Schuster-Boeckler, Chun-Xiao Song. Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base-resolution [J]. Nature Biotechnology, 2019, 1546-1696.

[6] Gao J, Feng Z, Wang X, Zeng M, Liu J, Han S, Xu J, Chen L, Cao K, Long J, Li Z, Shen W, Liu J. SIRT3/SOD2 controls osteoblast differentiation and bone formation by regulating mitochondrial stress[J]. Cell Death & Differentiation, 2017,25:229-240.

联系方式

chen122148@163.com


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